Score
Title
378
AskScience Panel of Scientists XVII
78237
Help us fight for net neutrality!
11142
From my kid: Can you put a marshmallow on a stick out into space and roast it with the sun?
16
What would our world look like if the collision which ejected the material from which formed the Moon had not occurred? Would there be liquid water? What kind of atmosphere if any? Active geological processes? Life?
4
[physics] When I turn off my oven but leave the door closed how does the temperature cool?
3
How accurate is the usual picture of the atomic nucleus of a ball/mass of protons and neutrons? What's really happening in the centre of atoms?
42
On my bike: is it more efficient to pedal fast in a low gear or slower in a high gear?
3
How would the government broadcast an emergency message in today's world where a majority of people watch tv through a streaming service?
1
If the Earth is closer to the sun for a part of the year, why isn't that summer MUCH hotter?
1
How do you define the number of conduction electrons?
10
What makes it "impossible" as of now to detect the hypothetical Graviton particle?
9
How are Muscle Knots / Trigger Points Created at the Cellular Level?
2
Can Dark Matter be explained by scale Invariance of empty space?
17
Is deep-earth nuclear fission heating the Earth's interior?
4
How in the world could a particle have a 1/2 spin value?
3371
Hein et al (2017) have explored scenarios for sending a spacecraft to the recently confirmed interstellar asteroid "Oumuamua". What payloads and capabilities would we wish to prioritize on the exploration of this strange and peculiar object?
11
How are doctors able to determine genetic abnormality in a fetus, by testing the mother’s blood?
11
Are all prime numbers smaller than the biggest prime number discovered?
10
What exactly is the Van Allen radiation belt?
6
Why children with adenoditis fall behind in their neurophychiatric development and do they recover in that aspect after the inflammation is gone?
12
Can blue light cause cancer? What about UVA? Where is the threshold?
4
When there is a momentum transfer between two charged particles (via a virtual particle) is that transfer instantaneous?
10
Do cephalopods control their camouflage consciously, if yes how exactly can an animals thought's change it's cells?
15
How does restricting Internet work?
11
Why can't powerbanks charge while being charged?
9
Is it a coincidence that the moons rotation around its axis matches the duration for its revolution around the earth? Or is there some scientific explanation on how these aligned in such a fashion?
7
Ask Anything Wednesday - Engineering, Mathematics, Computer Science
2
Are there any advantages to Removing Net Neutrality that the consumer can enjoy and not ISPs?
4
How does your body heal cuts?
6
How do they know 'Oumuamua is elongated vs of assymetric albedo? (Bonus Question: Is the assumed rotation stable?)
1
What changes when you break the sound barrier?
10
How, or why, do refraction and dispersion occur?
2
Are electrostatic interactions photon-mediated?
2
How does Lebesgue integral put Riemann integral and discrete sums in the same theorical mold ?
25
Why are radio waves and microwaves more damaging to the human body than light waves?
14
In my Psychology textbook it says that cortisol (a result of stress) reduces telomerase activity, therefore speeding up the aging process, however, I know that exercise also releases cortisol, yet is known to combat aging - how?
2
I measured an imaginary component of Earth's magnetic field?
3
Why does water behave like a mirror?
6
Why don't electrons in a superconductor radiate away their energy?
1
Why does the index of refraction of water change with temperature?
14
Why do planets orbit in planes?
63 holycripimacrapple The short answer is: none! The better answer is: Neuromuscular blocking drugs like atracurium, rocuronium, mivacurium etc act on the neuromuscular junction. They antagonise nicotinic acetylcholine receptors and this cause an inability to pass inputs from nerve to muscle cells (as opposed to suxamethonium which agonises the nictotinic receptors hence people twitch briefly after sux before paralysis sets in). Cardiac tissues do utilise acetylcholine but they have muscarinic receptors and as such the neuromuscular blockers have no effect. Cardiac tissue also has an intrinsic automaticity which organises cardiac impulses/beating. It is interesting that when you 'reverse' neuromuscular blockers with neostigmine (an acetylcholineesterase inhibitor) you get more acetylcholine available but not just at the neuromuscular junction, also in cardiac tissue. This means that neostigmine alone would cause a bradycardia (potentially significantly) and so we (almost) always give it with glycopyrrolate which causes a relative tachycardia. Source: Doctor in critical care/anaesthesia. Edit: please excuse any mistakes, just finished a long busy night shift! Edit 2: if you want some real detail here is a like to some stuff I used for my exams (sorry I don't know how to do pretty links!) http://www.frca.co.uk/article.aspx?articleid=100637
61 0 holycripimacrapple The short answer is: none! The better answer is: Neuromuscular blocking drugs like atracurium, rocuronium, mivacurium etc act on the neuromuscular junction. They antagonise nicotinic acetylcholine receptors and this cause an inability to pass inputs from nerve to muscle cells (as opposed to suxamethonium which agonises the nictotinic receptors hence people twitch briefly after sux before paralysis sets in). Cardiac tissues do utilise acetylcholine but they have muscarinic receptors and as such the neuromuscular blockers have no effect. Cardiac tissue also has an intrinsic automaticity which organises cardiac impulses/beating. It is interesting that when you 'reverse' neuromuscular blockers with neostigmine (an acetylcholineesterase inhibitor) you get more acetylcholine available but not just at the neuromuscular junction, also in cardiac tissue. This means that neostigmine alone would cause a bradycardia (potentially significantly) and so we (almost) always give it with glycopyrrolate which causes a relative tachycardia. Source: Doctor in critical care/anaesthesia. Edit: please excuse any mistakes, just finished a long busy night shift! Edit 2: if you want some real detail here is a like to some stuff I used for my exams (sorry I don't know how to do pretty links!) http://www.frca.co.uk/article.aspx?articleid=100637