Score
Title
260
AskScience Panel of Scientists XVIII
624
AskScience AMA Series: IAmA restoration ecologist focused on restoring oysters to the NY Harbor in New York City. AMA!
969
How does sunscreen stop you from getting burnt?
2844
How are drugs like antidepressants (who’s effects aren’t immediately apparent) developed?
5494
In the last 5-10 years, there’s been tremendous efforts made by many of the first world countries to curb carbon emissions. Have we made a dent?
8
Why does the space shuttle's transonic transition end so abruptly (see linked video)?
30
How do spacewalking astronauts get rid of body heat and CO2 they generate?
3
How does a catalyst affect activation energy?
3122
Why doesn't microwave energy escape through the holes in the screen of a microwave oven?
5
Why does the United States generally have a colder climate than most of Western Europe despite being at the same lattitude, and some parts even being further south?
15
How does the mind make up a physical feeling you've never experienced before while dreaming? For example, a virgin having a wet dream or having a foot amputated?
2
How often do collisions in LEO happen?
4
Why do people start to shrink once they get past a certain age?
3
Do bees have spatial memory when foraging for food?
7
How do we know the composition of Earth's core?
3
Suppose in an X speaking country, a child is raised by 2 parents; one speaks Y language around them, the other speaks Z language. What's the science behind this kid learning to differentiate all three languages and eventually being able to speak all 3, as opposed to if they were only exposed to 1?
25
Why does alcohol kill bacteria?
22
Why is the output power greater than the input power for a microwave?
5
Why do 3 polarising filters, at certain angles, allow some light through when two are at right-angles?
0
What happens do humans blood brain barrier as we age?
5
How do plants react to opiates? If I were to, say, use fentanyl as fertilizer, would the plant die? And what about other popular types of drugs, such as coke?
9
When can you consoder a organism dead?
2
Is chemical rocket exhaust usually a plasma?
12
Does hydraulic fracturing contribute to increased seismic activity(earthquakes) and how likely is it for the mix of chemicals+water ,that are used to displace the shale, to contaminate wells and body’s of water?
7
Why do car wheels look like they're rolling backward when moving fast?
4
Does everything rotate in space? If so, why?
2
Why don't lakes with streams flowing into other lakes eventually completely drain into the other lake?
9
Do animals have a really good sense of time or is it confirmation bias by humans?
10
What is the difference between an imaginary friend and a hallucination? What about Tulpas?
4
Where do scientists come up with temporal timelines for dinosaurs?
4987
This may be a stupid question, but what defines GMO. Is it simply changing a plant through cross pollinating (at its simplest level) such as Mendel, or does GMO mean laboratory tested and genetically altered through a laboratory?
14
What defines an “oil”?
136
Why is an Alpha particle denoted as a Helium atom?
0
When you pull at a slinky from the top, why does the bottom take a second to go with it?
3
a spider learns to build a net from other spiders or is it instinct ?
6
Why do molecules interact with others when they both have 8 valence electrons?
5
Is it more energy efficient to put cold water in a kettle, or hot water?
8
Do the planets in our solar system all orbit the sun on the same plane?
1
Which regions of the brain show diminished cell count with aging?
8
If Radiation is cumulative in our body, is Bluetooth (even with BLE) harmful to humans if we are constantly exposed to it with cellphones, smartwatch, etc. and also from other's electronic devices around us?
0
Can you feel the cold in space?
188
Are there any "weird" uses for heavy/transuranic elements?
6 lunchlady55 Almost all addictive drugs act on the brain’s natural reward circuitry, changing the way you feel, act and behave as you become increasingly dependent on the substance of your choice. When you drink an alcoholic beverage, inject heroin, take prescription painkillers or snort cocaine, these substances alter the way your brain processes chemicals called neurotransmitters. Each drug acts in a specific way to change the brain’s response to stimuli, but the end result is that the experience of using the substance is so pleasurable, relaxing or energizing that it triggers your internal reward system, making you want to repeat that experience again and again. Over time, your brain gets used to the response, and you need more of the drug to achieve the same euphoric, hallucinogenic or sedating effects. By this time, you may be displaying addictive behavior like: * Compulsively seeking the drug * Continuing to use the drug even though it’s obviously causing harm to you or your loved ones * Lying, stealing or doing other things that hurt your sense of integrity in order to get the drug * Taking dangerous risks in order to obtain or use the drug Blatantly stolen from the 3rd result of a Google search for "why are drugs addictive"
2 OhItsPreston Well, it depends on how in depth of an answer you're looking for. In general, the human brain is strongly wired to look for "reward", typically through activation of the dopamine pathway. These are dopamine (DA) producing neurons that extend from the ventral tegmental area (VTA) to other areas of the brain like the nucleus accumbens (NAc) and the prefrontal cortex (PFC). These DA pathways are generally activated by all sorts of "rewarding" stimuli that make you want them. Imagine anything that you anticipate, and that anticipation likely comes from DA. This could be food, sex, playing a videogame you've been looking forward to, the thought of a break from doing work, anything. It's a huge motivator and deeply ingrained in human biology. Almost all addictive drugs increase activity of the DA pathway, whether by increasing DA production, decreasing DA degradation, or lots of other mechanisms. This leads to individuals strongly seeking the source of the reward (the drug).
5 0 lunchlady55 Almost all addictive drugs act on the brain’s natural reward circuitry, changing the way you feel, act and behave as you become increasingly dependent on the substance of your choice. When you drink an alcoholic beverage, inject heroin, take prescription painkillers or snort cocaine, these substances alter the way your brain processes chemicals called neurotransmitters. Each drug acts in a specific way to change the brain’s response to stimuli, but the end result is that the experience of using the substance is so pleasurable, relaxing or energizing that it triggers your internal reward system, making you want to repeat that experience again and again. Over time, your brain gets used to the response, and you need more of the drug to achieve the same euphoric, hallucinogenic or sedating effects. By this time, you may be displaying addictive behavior like: * Compulsively seeking the drug * Continuing to use the drug even though it’s obviously causing harm to you or your loved ones * Lying, stealing or doing other things that hurt your sense of integrity in order to get the drug * Taking dangerous risks in order to obtain or use the drug Blatantly stolen from the 3rd result of a Google search for "why are drugs addictive"
2 0 OhItsPreston Well, it depends on how in depth of an answer you're looking for. In general, the human brain is strongly wired to look for "reward", typically through activation of the dopamine pathway. These are dopamine (DA) producing neurons that extend from the ventral tegmental area (VTA) to other areas of the brain like the nucleus accumbens (NAc) and the prefrontal cortex (PFC). These DA pathways are generally activated by all sorts of "rewarding" stimuli that make you want them. Imagine anything that you anticipate, and that anticipation likely comes from DA. This could be food, sex, playing a videogame you've been looking forward to, the thought of a break from doing work, anything. It's a huge motivator and deeply ingrained in human biology. Almost all addictive drugs increase activity of the DA pathway, whether by increasing DA production, decreasing DA degradation, or lots of other mechanisms. This leads to individuals strongly seeking the source of the reward (the drug).