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Tired of missing Science AMAs? Message u/ScienceAnnouncements to add your username to r/science's AMA Mailer!
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Science AMA Series: We are a group pf researchers that uses the MMO game Eve Online to identify Exoplanets in telescope data, we're Project Discovery: Exoplanets, Ask us Anything!
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NASA Mission AMA: We are scientists and engineers preparing for the OSIRIS-REx spacecraft’s Earth flyby tomorrow. Ask us anything!
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Scientists make atoms-thick Post-It notes for solar cells and circuits.
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Psychiatry Ignores an Elephant in the Room
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When forced to compete for mates, ducks develop extra long penises and others almost nothing at all.
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Thresholds of catastrophe in the Earth system
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Scientists say that a large, now extinct, frog called Beelzebufo that lived about 68 million years ago in Madagascar would have been capable of eating small dinosaurs. The conclusion comes from a study of the bite force of South American horned frogs.
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A New Test Can Detect Alzheimer’s Disease From The Blood
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High strength aluminum now 3D printable
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In a paper published Wednesday in the journal Science Advances, geophysicist Daniel Rothman illustrates how current rates of carbon emissions increases could trigger a sixth mass extinction by the year 2100.
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Thirst: Our brains tell us when to stop drinking
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Scientists map 10 sites where a special sugar known as O-GlcNAc is added to the protein OCT4, one of the core Yamanaka factors critical for pluripotency of stem cells. O-GlcNAylation of OCT 4 ultimately regulates transcriptional activity at variety of promoters.
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Detecting Proxima b's atmosphere with the James Webb Space Telescope
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Possible cause for some forms of autism? Maternal gut bacteria promote neuro-developmental abnormalities in mouse offspring
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Reliance on ‘gut feelings’ linked to belief in fake news, study finds Political bias isn’t all that shapes how we perceive truth
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Looking at cell metabolism instead of histology, EPFL scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma, a liver cancer in children.
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Scientists discover an underwater octopus city. Dub it 'Octlantis'.
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Study suggests you can ‘pick up’ a good or bad mood from your friends
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Researchers think a full 'bodyNET' is the platform of the future
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PTSD Associated with Increased Lupus Risk
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Nicotine in e-cigs: addictive, increases your risk of heart disease
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Emission budgets and pathways consistent with limiting warming to 1.5°C
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Phylogenetic analysis demonstrates that a change in braincase morphology in the sauropod lineage correlates with a herbivorous diet, not quadrupedality as previously assumed.
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Poor diet kills one in five of us - The New Food Economy
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Alcohol Use Affects Levels of Cholesterol Regulator through Epigenetics
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Thresholds of catastrophe in the Earth system
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Losers are more likely to believe in conspiracy theories, study finds
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Combining HIV antibodies may stop more strains of HIV than any single one can do alone, two new studies in monkeys suggest. Both combinations showed "impressive protection" and prevented infection from multiple strains of an HIV-like virus.
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Thunderstorm Turns Into a Nuclear Reactor and Blasts Radiation Everywhere
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Genome editing reveals a role for OCT4 in human embryogenesis
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Gene silencing works in humans: Alnylam releases Phase III clinical trial data showing therapeutic benefit, paving the way for the first siRNA gene silencing drug
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A slow-cycling subpopulation of melanoma cells with highly invasive properties
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Study Calculates Death Rate During Triathlons at 1.74 per 100,000 Participants. This May Seem Low, But it is 1000 Times the Background Rate.
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The environmental footprint of conservationists found to be similar to that of comparable groups of medics and economists.
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Across five experiments, new paper shows that dehumanization—the act of perceiving victims as not completely human—increases instrumental (where victims are harmed to achieve instrumental goals), but not moral (harm is perceived as morally righteous) violence.
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A 40-year study of teens finds Generation Z avoids sex, alcohol, and driving at record rates
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Great Lakes Defenders Have a Shocking Idea to Stave Off Invasive Carp
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Researchers Develop Solar Cells That Can Be Sewn Onto Clothing: First-time demonstration of achieving high-performance, high-efficiency energy conversion, and waterproof properties and stretchability, as published in Nature Energy
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Researchers at UC San Francisco have discovered Gut Microbes May Influence Multiple Sclerosis Progression
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Bite force in the horned frog (Ceratophrys cranwelli) with implications for extinct giant frogs
109 SpecterGT260 Ok so hold up here: If you read the full text article these guys took some neuron stem cell lines and infected them with toxoplasma gondii. Then they did a ridiculously in depth gene and protein-level analysis and looked at changes in genes that have been implicated in these diseases. The analysis is crazy deep because that's what proteomics and bioinformatics is but it's really an associative analysis of an artificial state. The word "modulates" in their title is also interesting as it doesn't seem that the researchers have even established whether these changes are good or bad. They just know they are different. Basically, "we infected brain cells with a parasite and the cells started producing different levels of proteins, some of which have been associated with known diseases" This does NOT mean that your family member with Parkinson's or Alzheimer's had a toxo infection. This does NOT mean that treating your family member for toxo will help them get better Edit: words are hard
41 RespectMyAuthoriteh The parasite is *Toxoplasma gondii* [saved you a click].
9 anonymous-coward If this were significant, then the USA should have a relatively low incidence of Alzheimer's ([9.1% Toxo seroprevalence among 15-44 age group](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047742/)), and Germany should be much higher ([77% antibodies in 70-79 age group, and 20% in 18-29](https://www.nature.com/articles/srep22551)). But it seems that the [US has a far higher Alzheimer's death rate](http://www.worldlifeexpectancy.com/cause-of-death/alzheimers-dementia/by-country/), despite the German population being top-heavy. Probably there are differing definitions of 'death by Alzheimer', though.
7 [deleted] [removed]
2 Abscess2 "The team then applied what they describe as a reconstruction and deconvolution approach to identify connections between T. gondii infection and altered pathways in neurodegenerative diseases, as well as connections between toxoplasmosis, human brain disorders, and some cancers. "Our results provide insights into mechanisms whereby this parasite could cause these associated diseases under some circumstances," the authors wrote. “This work provides a systems roadmap to design medicines and vaccines to repair and prevent neuropathologic effects of T. gondii infection of the human brain. Furthermore, our original template provides a novel method to integrate multiple levels of intrinsic and extrinsic factors highlighting a way to unravel complexity in brain parasitism, toxoplasmosis specifically, and other complex diseases.”
2 Shodan30 Wasn't this a stargaze:atlantis episode
2 MinxManor Interesting. I have read that Toxoplasmosis can cause a type of Schizophrenia and also a type of early cataract.
2 Candicebush I bet most people with cancer have had the flu, and mono, and the common cold.
2 zimzam911 I would like to see a study about toxoplasma gondii and human sexual orientation.
2 _pinkpajamas_ How does one pursue testing for this? I have a friend who I've always suspected may have this. She's a feral cat rescuer.
1 Antimutt I understand there's a high incidence in France, due to their like of cats perhaps? I'd also be interested in knowing rates in the aboriginal population of Australia, for some bushmen are also known to like cat.
1 OliverSparrow Wouldn't that predict early and universal death for cat owners? Against all evidence? So you read the article and find that in vitro cells exposed to the parasite produce some anomalous proteins that are indirectly associated with the conditions mentioned. Yeah, well... Once we had salami slicing. Now we have click bait press releases. Academia is turning into a weak parody of commerce at its most vapourware-vending.