Science AMA Series: How Do Doctors Learn Anatomy? I'm Chris Ruff, from Johns Hopkins, I've taught anatomy for 35 years, AMA!
A new study on the personal values of Trump supporters suggests they have little interest in altruism but do seek power over others, are motivated by wealth, and prefer conformity. The findings were published in the journal Personality and Individual Differences.
Autism's social deficits are reversed by an anti-cancer drug. Using an epigenetic mechanism, romidepsin restored gene expression and alleviated social deficits in animal models of autism
Self-employed people are happier and more engaged at work despite working longer hours and having less job security, according to a study of 5,000 workers
The United States spent approximately twice as much as other high-income countries on medical care, yet utilization rates were largely similar to those in other nations. Prices of labor and goods, including pharmaceuticals and devices, and administrative costs appeared to be main drivers - JAMA
A new study finds that listening to motivational music during sport activities increases risk-taking behavior but does not improve overall performance.
Teenagers are more likely to plead guilty to crimes they did not commit because they are less able to make mature decisions, new research shows. Other research has found adolescents are less able to perceive risk and resist the influence of peers because of developmental immaturity.
Astronomers nearly doubled the previous record for a distance measurement within our galaxy, which paves the way for a full galactic map. By using natural Masars, the team determined the distance to a star-forming region on the far side of the Milky Way, some 66,000 light-years away.
Asteroids and comets provide Mars with 30% of its organic material. Lead author: “Near other stars, there are also exo-asteroids and exo-comets that can shower the surfaces of exoplanets with carbon. If, on top of that, there is water, then you have the required ingredients for life."
Sexual-minority students more likely to abandon science majors: Undergraduates who identify as gay, lesbian, bisexual or queer switch to non-science degrees at higher rates than their heterosexual peers
Mars’ oceans formed early, possibly aided by massive volcanic eruptions
Men and women with depression experience opposite genetic changes and may need different forms of treatment, researchers discover
Landmark Report Concludes Abortion In U.S. Is Safe -- "The report also says nurse practitioners and physician assistants can perform abortions just as safely as physicians. Also, abortions have no long-term consequences on women's physical and mental health"
Adults’ Political Leanings Linked With Early Personality Traits. Studies indicate that children who showed higher levels of conduct problems — that is, aggression, fighting, stealing from peers — were more likely to be economically left leaning and distrustful of the political system as adults
Changes in the sense of taste and smell are a common side-effect experienced by patients being treated for cancer. Changes in these senses can affect food preferences and food intake of the patient. Therefore, eating healthy and tasteful might become a problem for cancer patients.
New Study: Dogs Prefer You Talk to Them in 'Dog Talk'
Cafestol, a Bioactive Substance in Coffee, Has Antidiabetic Properties
After reconstructing over 150 years of tree growth in the Indian Himalayas, University of Geneva researchers have found that rising temperatures are increasing avalanche frequency, size and scope.
Predator-secreted sulfolipids induce defensive responses in C. elegans
Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children
VC Stereotypes About Men and Women Aren’t Supported by Performance Data
A study has found that in order to build the Great Pyramids Egyptians created points-of-reference using the sun during the autumn equinox - a day halfway between the summer and winter solstices when day and night are of equal length.
Pain's Origins May Be Significantly Different in Males and Females - "New research from The University of Texas at Dallas supports the growing consensus that pain begins differently for men and women at the cellular level."
Lead is even deadlier than we feared as the full extent of its toxic effects are revealed
Solenodon: This bizarre venomous mammal that survived the asteroid that killed the dinosaurs has had its genome sequenced for the first time. Scientists found the genus most likely diverged from other living mammals around 73.6 million years ago, before the devastating asteroid impact.
Chain reaction of fast-draining lakes poses new risk for Greenland ice sheet
American Psychopaths And Dutch Psychopaths Display Different Personality Traits. Whereas “callousness” and “lack of empathy” seem to be the defining characteristics of your typical American psychopath, Dutch psychopaths are better recognized for their “irresponsibility” and “parasitic lifestyle”.
Resilience with Mixed Agricultural and Urban Land Uses in Tokyo, Japan
Teens who are old for their grade appear to feel more confident about their academic abilities and are more likely to enroll in college than their younger peers, according to research published by the American Psychological Association.
Researchers have fused living and non-living cells for the first time in a way that allows them to work together, paving the way for new applications. The system, created by a team from Imperial College London, encapsulates biological cells within an artificial cell.
Cannabidiol significantly reduces seizure frequency and duration in patients with seizures associated with Lennox-Gastaut syndrome: a randomised, double-blind, placebo-controlled phase 3 trial
A Systematic Review Shows How to Maintain Sexual Desire in a Relationship. Studies show that partners must both feel attractive and be attracted to their significant others. This encompasses emotional and physical facets. Emotionally, confidence and attentiveness factor most into attraction.
Space Radiation is Increasingly More Hazardous - Radiation dose rates over last four years exceeded trends from previous solar cycles by at least 30%, showing that the radiation environment is getting far more intense, with implications for future missions to the moon, Mars, asteroids and beyond.
A new systematic review, now published in the Harvard Review of Psychiatry, found that people living in high-altitude areas of the United States, such as intermountain states, have higher-than-average rates of suicide and depression.
Environment dominates over genetics in shaping human gut microbiota
Bomb Cyclones, Nor’easters, and the Messy Relationship Between Weather and Climate
During the hours of sleep the memory performs a cleaning shift: a study reveals that when mice sleep, the neural connections that collect important information are strengthened and those created from irrelevant data are weakened until they get lost.
Cell therapy for Alzheimer's disease - Inhibitory interneurons are particularly important for managing brain rhythms. Researchers have uncovered the therapeutic benefits of genetically improving these interneurons and transplanting them into the brain of a mouse model of Alzheimer's disease.
Is 60 the New 50? Older Americans are experiencing ‘delayed aging’ — and better health: Americans may be aging more slowly than they were two decades ago.
BY analyzing a prehistoric site in the Libyan desert, a team of researchers has been able to establish that people in Saharan Africa were cultivating and storing wild cereals 10,000 years ago.
Yale Study: Sad, Lonely Introverts Are Natural Born Social Psychologists: Introverts prone to melancholy are exceptionally good at accurately assessing truths about human social behavior, without formal training or tools.
273 LIGHT130 How promising is this? Is this just a theoretical future treatment that we won’t hear more from for years or is this very promising ?
149 lYossarian I have never once in my entire life heard it referred to as "The horse of Troy". I get that a Trojan is a resident of Troy but the way it's phrased reminds me of saying something like "Fries from France" or "a rug from the Orient".
37 _Scrumtrulescent_ I feel like I see a new treatment for cancer every month that seems extremely promising and yet I've never heard them brought up again. Does it take that long to see if it works for humans or do they all just fail? It boggles my mind that there isn't an established fure yet for at least a few kinds of cancer at this point. For the record I understand human trials take a long time before anything is approved to go to market, but I remember hearing stories like this years ago and still never a follow up as to whether it went as expected or if it failed completely (or anything inbeween).
6 TheSupernaturalist So this seems like a very promising treatment, but it isn't perfect. So the treatment doesn't find cancer cells, it is a lipid-membrane with a cellular "factory" that contains the ability to create a protein that destroys the cell. The significance of this is that it only creates the protein when it detects that it is inside a cancer cell (how it does this the article didn't say). The issue arises because it seems like this membrane incorporates itself into any cell it can, not just cancer cells and we need to know what the implications of that might be. Overall incredible idea and props to the team that made this happen. I can't imagine all the work that went into designing and creating this.
11 mvea The title of the post is a cut and paste from the first paragraph of the linked popular press article here: > Like the horse of Troy, scientists at the Technion have developed a way to sneak synthetic cells right into tumor tissue, where they then begin producing cancer-fighting proteins from the inside. The technique was tested in both cell cultures and in mice, and found to be an effective treatment in both cases. For those interested here is a link to the academic press release: Journal reference: N. Krinsky, M. Kaduri, A. Zinger, J. Shainsky-Roitman, M. Goldfeder, I. Benhar, D. Hershkovitz, A. Schroeder, Synthetic Cells Synthesize Therapeutic Proteins inside Tumors Adv. Healthcare Mater. 2017, 1701163. DOI: Link: Abstract > Synthetic cells, artificial cell-like particles, capable of autonomously synthesizing RNA and proteins based on a DNA template, are emerging platforms for studying cellular functions and for revealing the origins-of-life. Here, it is shown for the first time that artificial lipid-based vesicles, containing the molecular machinery necessary for transcription and translation, can be used to synthesize anticancer proteins inside tumors. The synthetic cells are engineered as stand-alone systems, sourcing nutrients from their biological microenvironment to trigger protein synthesis. When pre-loaded with template DNA, amino acids and energy-supplying molecules, up to 2 × 107 copies of green fluorescent protein are synthesized in each synthetic cell. A variety of proteins, having molecular weights reaching 66 kDa and with diagnostic and therapeutic activities, are synthesized inside the particles. Incubating synthetic cells, encoded to secrete Pseudomonas exotoxin A (PE) with 4T1 breast cancer cells in culture, resulted in killing of most of the malignant cells. In mice bearing 4T1 tumors, histological evaluation of the tumor tissue after a local injection of PE-producing particles indicates robust apoptosis. Synthetic cells are new platforms for synthesizing therapeutic proteins on-demand in diseased tissues.
2 Zimited I don’t have the experience to understand much that’s happening here, but this seems like really good news, right?