The article does not say what a healthier diet is so what did they measure against? I would say a low carb high fat diet is healthy. But I wonder what they think is healthy.
This bit is interesting:
>“It has only recently been discovered that the innate immune system has a form of memory”, explains Prof. Dr. Eicke Latz, Director of the Institute for Innate Immunity of the University of Bonn and scientist at the DZNE. “After an infection, the body's defenses remain in a kind of alarm state, so that they can respond more quickly to a new attack.” Experts call this “innate immune training”. In the mice, this process was not triggered by a bacterium, but by an unhealthy diet.
>The scientists were further able to identify the responsible “fast food sensor” in immune cells.
Wonder if this has to do with the whole Neu5Gc theory that's been posited for years. Eat too much meat and you develop inflammatory responses to Neu5Gc which is found in mammals except humans. This special sugar found in meat gets incorporated onto your cells, which your body thinks is unnatural, and causes an inflammatory response. Wonder if 'unhealthy' diets here also meant more meat. High-fat, high sugar doesn't really mean much.
The problem is that mouse, dog, even monkey models will fail to capture these effects since they all see Neu5Gc as natural while in humans it isn't. Immune systems in humans are completely different than even that of our closest relative the chimp.
>The scientists placed mice for a month on a so-called “Western diet”: high in fat, high in sugar, and low in fiber. The animals consequently developed a strong inflammatory response throughout the body, almost like after infection with dangerous bacteria.
wow - a whole month and they didn't bother to eliminate any aspect like sugar/carbs or fats to narrow down things to the real cause... good thorough job there science!
Probably not relevant to humans as we evolved eating WAY more fat than mice did.